Articles » IV International Conference. Modern Aspects of Rehabilitation in Medicine.
IV International Conference. Modern Aspects of Rehabilitation in Medicine.
As you know one of adverse effects of antibacterial therapy of chronic infectious inflammatory diseases with concomitant secondary immunodeficiency is development of antibiotic induced intestinal dysbacteriosis, severity of which predetermines effectiveness of therapy and outcome of disease to a large extent.
For the purposes of indirect prophylaxis of antibiotic induced intestinal dysbacteriosis in patients with chronic obstructive pulmonary disease (COPD) we used biologically active food additives: EnergoIod containing high concentrations of organic iodine with essential microelements and Transfer Factor being a traditional universal peptide immunocorrector.
Protective effect of the used preparations against disturbance of microbiocenosis in large bowel was recognized as statistically significant in case of significant (2.7-3.0 times) reduction in clinical symptoms of dysbacteriosis such as pain and discomfort in the lower belly, dysperistalsis (rumbling, flatulence), irregular bowel movements (frequent or constipation), liquid or shapeless stool, plugs in stool and incomplete bowel emptying. Results of microbiological study of fecal samples showed that on the 15th day of antibacterial therapy in experimental group only 1/3 of patients had dysbacteriosis of large bowel of 1 degree and 10% of patients had moderate dysbacteriosis.
At the same time in the control group of patients undergoing basal therapy microbiological manifestations of dysbacteriosis were observed in 60% of patients, 33.3% had moderate and 5.0% - severe disturbance of microbiocenosis. Intestinal dysbacteriosis was characterized by reduction in quantity of full-value colon bacillus, bifid bacteria and lactic acid bacilli, prevalence of coccus forms over bacilli, appearance of escherichias with pathologic properties, increase in content of opportunistic enterobacteria, hemolytic forms of microorganisms, Proteus bacteria and Candida yeast-like fungi.