Action spectrum » Immunomodulating Activity
Immunomodulaing activity means the preparation’s ability to restore disturbed functions of human immune system.
People are affected by numerous adverse environmental factors which put additional load on human organism, in particular immune system. Contaminants of any type are oxidizers which promote generation of such substances as oxygen free radicals (OFR) and products of lipid peroxidation (PLP) in cells biomembranes which are dangerous to human organism. Oxidizing reactions involving generation of free radicals are induced also by stress factors. PLP and OFR are extremely dangerous substances able to damage essential molecules and cellular structures and to disturb metabolic processes. Their continued effect results in reduction of organism’s ability to resist, increased incidence of chronic diseases, oncological pathologies, allergic diseases and immunodeficiency disorders.
EnergoIod Concentrate is destined for maintaining organism’s nonspecific resistance and ensuring its protection against premature aging.
Affecting human cells EnergoIod changes the range of cytokines generated by cells. New cytokines make human cells’ able to resist infections effectively. It was proven by example of human cells infected in vitro with the viruses of encephalomyocarditis, herpetic fever of type I and herpetic fever of type II.
Evoking changes in the range of generated cytokines (these are small peptide information molecules ensuring integrity of immune, endocrine and nervous systems) EnergoIod preparation enhances functional activity of human cells. Such effect on fibroblasts and epithelial cells leads not only to enhancement of dentoepithelial tissues’ ability to resist infections but also to enhancement of their regeneration ability (recovery of wounds, erosions and ulcers).
Enhancing functional activity of immune system’s cells EnergoIod concentrate activates organism’s immune protection. In particular this preparation induces alpha-, beta- and gamma- interferons, activates heterophilic leukocytes, attracts monocytes (macrophages) to the inflamed area, and enhances synthesis of immune bodies which resist antigens. In patients with weak immunity EnergoIod restores cells in depleted populations of leucocytes and lymphocytes in full or in part, improves weakened functions of separate segments of immunity and immune system as a whole.
EnergoIod Concentrate is effective in treatment of diseases with underlying pathologies of antibody production, i.e. when blood contains increased number of damaging immune complexes or antibodies responsible for allergy (such diseases are frequent nowadays: bronchial asthma, eczema, inflammations of joints and kidneys, chronic hepatitis etc.).
EnergoIod Concentrate promotes restoration of immunity, affects favourably hematopoiesis, cerebral circulation, functions of liver, gastrointestinal system, kidneys, relieves symptoms of allergic diseases, promotes elimination of toxins and radionuclides from organism.
Results of studies show that this preparations shows favorable effects in correction of various defects connected with reduced immune reactions (postradiational damage, chronic inflammatory diseases of viral and bacterial origin) and with excessive activity of particular immune segments (nonspecific ulcerative colitis, disseminated sclerosis, rheumatic arthritis). Thus immunomodulating effect of EnergoIod is based on activation of cell-bound and humoral immunity. In patients with weak immunity EnergoIod restores cells in depleted populations of leucocytes and lymphocytes in full or in part, improves weakened functions of separate immune segments and immune system as a whole.
Topical action
EnergoIod Gel id absorbed easily by epithelial cells and mucosa, that is why it can activate effectively local immunity, more exactly it can effectively enhance tissues’ ability of resisting infections and regenerating. Distinctive feature of this preparation is possibility of topical administration (in contrast to majority of immunomodulators which are effective only when administered systemically).
Data obtained in studies of immunomodulating properties of gel and concentrate EnergoIod indicative of their stimulating effect on immune protection mechanisms allow to regard these preparations as promising immunomodulators.